One gene, one enzyme theory

Japanese: 一遺伝子一酵素説 - いちいでんしいちこうそせつ(英語表記)one gene-one enzyme theory
One gene, one enzyme theory
The hypothesis that one enzyme is under the control of one gene. In 1945, American scientists Beadle and Tatum inferred this when studying a mutant strain of Neurospora crassa, which lacked the enzymes that catalyze each reaction in the arginine synthesis pathway. In response to this, some people praise the one-gene-one-peptide-chain hypothesis, arguing that genes do not necessarily synthesize enzymes.

Source: Encyclopaedia Britannica Concise Encyclopedia About Encyclopaedia Britannica Concise Encyclopedia Information

Japanese:
一つの酵素は一つの遺伝子の支配下にあるという仮説。 1945年にアメリカのビードルとテータムが,アカパンカビの突然変異種を研究中,アルギニン合成経路のそれぞれの反応を触媒する酵素が欠如していることから推論した。これに対し,遺伝子が合成するのは必ずしも酵素とは限らないとして,一遺伝子一ペプチド鎖説を称える者もある。

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