…It was discovered in the 1920s by muscle biochemists O. Meyerhof and K. Lohmann in the muscles of crustaceans, and has since been found in the muscles of many invertebrates. As a high-energy phosphate ester, it plays a role in storing and transporting energy in the body, similar to creatine phosphate in vertebrates. … From [High Energy Bonds]…The energy stored in the form of ATP's high-energy bonds is used to synthesize various high-energy compounds and, in turn, drives many biosynthetic reactions, but is also converted into physical energy such as mechanical work (motion) and osmotic work (active transport). The concept of high-energy bonds was proposed by K. Lohmann and O. Meyerhof (1934), but the credit for clearly defining its biological significance goes to F. Lipmann (1941). ATP [Masao Kawakita]. … *Some of the terminology that mentions "Meyerhof, O." is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…筋肉生化学の大家マイヤーホーフO.MeyerhofとローマンK.Lohmannによって1920年代に甲殻類の筋肉から発見され,その後多くの無脊椎動物の筋肉中に見いだされている物質。脊椎動物におけるクレアチンリン酸と同様に高エネルギーリン酸エステルとして,生体内でエネルギーの貯蔵と運搬の役割を担っている。… 【高エネルギー結合】より…こうしてATPの高エネルギー結合の形でいったん貯蔵されたエネルギーは,種々の高エネルギー化合物の合成に利用され,さらに転じて多くの生合成反応を駆動するが,また一方機械的仕事(運動)や浸透圧的仕事(能動輸送)などの物理的エネルギーにも転換される。高エネルギー結合の概念の提唱者はローマンK.LohmannとマイヤーホーフO.Meyerhof(1934)であるが,その生物学的意義を明確に定式化した功績はリップマンF.A.Lipmann(1941)に帰せられる。ATP【川喜田 正夫】。… ※「Meyerhof,O.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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