…In Japan, there are few cases of folic acid deficiency, and many cases of vitamin B12 deficiency, with pernicious anemia being the most common. Pernicious anemia is a condition in which the secretion of a glycoprotein called intrinsic factor , which is secreted by the gastric mucosa and binds with vitamin B12 before being transported through the intestinal tract and absorbed in the lower part of the small intestine, decreases, causing vitamin B12 deficiency in the body and resulting in megaloblastic anemia. One type of megaloblastic anemia. … *Some of the terminology that mentions "pernicious anemia" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…日本では,葉酸欠乏によるものは少なく,ビタミンB12欠乏によるものが多いが,なかでも悪性貧血が多い。 悪性貧血pernicious anemia胃粘膜で分泌されビタミンB12と結合して腸管内を運ばれ小腸下部でビタミンB12が吸収されるのに必要な内因子とよばれる糖タンパク質の分泌が低下するために,体内のビタミンB12欠乏を生じ巨赤芽球性貧血を起こすもの。巨赤芽球性貧血の一つ。… ※「pernicious anemia」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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