…The pH of body fluids is normally maintained at 7.4, mainly due to the action of the carbonate buffer system, which is based on the equilibrium between carbon dioxide (acidic) and bicarbonate (alkaline). However, when the ventilation function of the lungs deteriorates due to respiratory disease or a decrease in the function of the respiratory center, the partial pressure of carbon dioxide in the blood increases and the pH decreases (this is called respiratory acidosis). On the other hand, in cases of uremia, diabetic ketosis, diarrhea, shock, etc., excessive acid production, loss of base, or decreased acid excretion occurs, resulting in a decrease in bicarbonate ions in the blood and a decrease in pH (this is called metabolic acidosis). … *Some of the terminology that refers to "respiratory acidosis" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…体液のpHは,主として炭酸(酸性)と重炭酸(アルカリ性)の平衡による炭酸緩衝系の作用で,正常では7.4に保持されている。ところが,呼吸器の病気や呼吸中枢の機能低下により,肺の換気機能が悪くなると,血液の炭酸ガス分圧が上昇し,pHは低下する(これを呼吸性アシドーシスrespiratory acidosisという)。一方,尿毒症,糖尿病性ケトーシス,下痢,ショックなどでは,酸の産生の過剰,塩基の喪失,または酸の排出の低下が起こり,血液の重炭酸イオンが低下し,pHは低下する(これを代謝性アシドーシスmetabolic acidosisという)。… ※「respiratory acidosis」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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