…In other words, muscle contraction is regulated by the increase or decrease of minute amounts of Ca2 + around myofilaments. Inside skeletal muscle fibers, there is a developed sac-like membrane structure called the sarcoplasmic reticulum, which has the property of taking in Ca2 + into its lumen. For this reason, most of the Ca2 + in muscle fibers at rest is taken up into the lumen of the sarcoplasmic reticulum, and the Ca2 + concentration around myofilaments is only 10-7 mol or less. … From [Endoplasmic Reticulum]...The rough endoplasmic reticulum is often continuous with the nuclear membrane, and the secretory proteins produced by ribosomes on the rough endoplasmic reticulum enter the smooth endoplasmic reticulum and are secreted outside the cell through the endoplasmic reticulum (including the Golgi apparatus) scattered vertically and horizontally within the cell. The endoplasmic reticulum of muscle cells is a specially differentiated smooth endoplasmic reticulum called the sarcoplasmic reticulum, which regulates muscle contraction and relaxation by releasing and taking in Ca2 + into the cytoplasm. Cells [Takeda Fumikazu]. ... *Some of the terminology that mentions "sarcoplasmic reticulum" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…つまり筋収縮は,筋フィラメントのまわりの微量のCa2+の増減によって調節される。骨格筋繊維の内部には筋小胞体sarcoplasmic reticulumという袋状の膜構造が発達しており,その内腔にCa2+をとり込む性質がある。このため静止状態の筋繊維内のCa2+は大部分筋小胞体内腔にとり込まれており,筋フィラメント周囲のCa2+濃度は10-7mol以下にすぎない。… 【小胞体】より…粗面小胞体は核膜と連続しているときが多く,粗面小胞体上のリボソームで作られたタンパク質の分泌物質は滑面小胞体に入り,細胞内に縦横に散在する小胞体(ゴルジ体を含めて)を通って細胞外に分泌される。筋肉細胞の小胞体は特殊に分化した滑面小胞体で,筋小胞体sarcoplasmic reticulumと呼ばれ,Ca2+の細胞質への放出,取込みで筋の収縮,弛緩の調節を行っている。細胞【武田 文和】。… ※「sarcoplasmic reticulum」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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