…For this reason, in recent years, there have been many attempts to turn wild and domestic animals into laboratory animals. Laboratory animals are divided into inbred lines, closed colonies, cross breds, etc., depending on the strength of their genetic management. Inbred lines are strains that have been repeatedly crossed between full siblings for more than 20 generations, and are a group with no genetic variation at all, with almost all individuals considered to be completely homozygous. … From [Pure line]…In fact, in many self-pollinating crops, many pure lines are created, and superior lines are selected from them to be used as new varieties. In laboratory animals and cross-fertilizing plants, repeated inbreeding such as brother-sister mating creates inbred lines that are far from pure lines but have advanced homozygosity at many gene loci, and these are used for breeding and experiments. [Onishi Omi]. … *Some of the terminology that mentions "inbred line" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…そのため,近年,野生動物や家畜から実験動物化する試みが盛んに行われている。 実験動物はその遺伝管理の強さによって近交系inbred line,クローズドコロニーclosed colony,交雑群cross bredなどに分けられる。近交系と呼ばれるものは20世代以上,全兄妹間の交配を繰り返した系統で,遺伝的にはほとんど完全なホモ接合体の個体ばかりと考えられる遺伝的変異のまったくない集団である。… 【純系】より…実際多くの自殖性作物で,多数の純系を作り,その中から優れた系統を選び出し,新しい品種として用いている。実験動物や他家受精する植物では,兄弟姉妹交配などの近親交配を繰り返すことにより,純系にはほど遠いが多くの遺伝子座でホモ接合化が進んだ近交系inbred lineが作られ,育種や実験に用いられている。【大西 近江】。… ※「inbred line」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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