Growth hormone inhibiting factor

...A hormone consisting of 14 amino acids, it was isolated and identified in 1973 by Brazeau P. Brazeau et al. from an extract of 500,000 sheep hypothalamus. Since it inhibits the secretion of growth hormone (also known as somatotropin), it is also called growth hormone inhibiting factor (abbreviated as GIF), growth hormone inhibiting hormone (GIH), or somatotropin release inhibiting factor (SRIF). Somatostatin inhibits not only growth hormone, but also the secretion of thyroid-stimulating hormone (TSH) from the pituitary gland, and also inhibits the secretion of hormones such as insulin, glucagon, and gastrin from the pancreas and digestive tract. ...

*Some of the terminology that refers to "growth hormone inhibiting factor" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

…14個のアミノ酸からなるホルモンで，1973年ブラゾーP.Brazeauらによって，50万個のヒツジの視床下部の抽出物から分離，同定された。成長ホルモン(別名ソマトトロピン)の分泌を抑制することから，成長ホルモン放出抑制因子growth hormone inhibiting factor(GIFと略記)，growth hormone inhibiting hormone(GIH)，somatotropin release inhibiting factor(SRIF)とも呼ばれる。ソマトスタチンは，成長ホルモンだけでなく，脳下垂体からの甲状腺刺激ホルモン(TSH)の分泌を抑制し，さらにインシュリンやグルカゴン，ガストリンなど，膵臓や消化管からのホルモンの分泌を抑える作用ももつ。…

※「growth hormone inhibiting factor」について言及している用語解説の一部を掲載しています。

出典｜株式会社平凡社世界大百科事典 第２版について | 情報