Centrilobular emphysema

Japanese: centrilobular emphysema(英語表記)centrilobularemphysema
Centrilobular emphysema

Emphysema is classified into three types based on histological morphology: centrilobular emphysema, which is caused by the destruction and enlargement of the respiratory bronchioles in the center of the lobule; panlobular emphysema, which is caused by the destruction and enlargement of the alveolar passages and alveolar sacs; and focal emphysema, which occurs in an isolated area around a scar or under the pleura.
[Causes, symptoms, etc.]
The majority of clinically observed emphysema cases are in middle-aged and elderly people who are heavy smokers, and are more common in men, with a centrilobular pattern.

*Some of the terminology that mentions "centrilobular emphysema" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

… 肺気腫は組織形態のうえからは三つに分類される。すなわち,小葉の中心部にある呼吸細気管支が破壊され拡大する小葉中心型肺気腫centrilobular emphysema,肺胞道や肺胞囊の破壊を伴った拡大を示す汎小葉型肺気腫panlobular emphysema,瘢痕(はんこん)の周囲や胸膜下に孤立性に生じる巣状型肺気腫focal emphysemaである。
[成因,症状など]
 臨床上みられる肺気腫症の大部分は高度喫煙者の中高年者であり,男子に多く,小葉中心型を示す。…

※「centrilobular emphysema」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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