...However, because of the confusion, the former is now called anti-anxiety drug and the latter anti-psychotic drug. The first anti-anxiety drug was meprobamate, which was synthesized by F.M. Berger as a muscle relaxant and was found to have an anxiolytic effect (1955). This was followed by the benzodiazepines chlordiazepoxide, diazepam, oxazepam, and others, which are widely used for psychosomatic disorders. These drugs cause muscle relaxation and drowsiness, making it dangerous to drive a car after taking them. *Some of the terminology that mentions "Berger, FM" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…しかし,まぎらわしいので現在では,前者を抗不安薬anti‐anxiety drug,後者を抗精神病薬anti‐psychotic drugとよぶようになった。バーガーF.M.Bergerが筋弛緩薬として合成したメプロバメートに抗不安作用が発見された(1955)のが最初の抗不安薬で,次いでベンゾダイアゼピン系のクロルジアゼポキサイド,ジアゼパム,オキサゼパムなどが合成され,心身症などに広く用いられている。これらは筋弛緩や眠気などを伴うので,服用後の自動車運転は危険である。… ※「Berger,F.M.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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