Discoloration caused by the deposition of foreign or self-produced substances in living tissues. Examples of discoloration caused by foreign substances include anthracosis (blackening of the lungs and lymph nodes), argyria (graying of the skin, mucous membranes, and internal organs due to the ingestion of silver nitrate), lead poisoning (lead sulfide deposition in the gums due to the use of cosmetics containing lead), and tattooing. Examples of autologous substances include the black pigment melanin (freckles, moles, malignant melanoma), the brown pigment lipofuscin deposition (atrophic organs), hemoglobin (physiologically or after a large blood transfusion, hemoglobin breaks down and iron-containing pigments are deposited), and bile pigments (jaundice). Source: Heibonsha World Encyclopedia, 2nd Edition Information |
外来性の物質あるいは自己の産生する物質が生体組織に沈着し変色すること。外来物質によっておこるものには炭粉沈着症(肺,リンパ節が黒色化),銀沈着症(硝酸銀の服用で皮膚,粘膜,内臓が灰色化),鉛(なまりえん)(鉛を含む化粧品の使用で歯肉に硫化鉛が沈着),また入墨がある。自己の物質では,黒色色素のメラニン(そばかす,ほくろ,悪性黒色腫),褐色色素リポフスチンの沈着(萎縮性臓器),血色素(生理的に,あるいは多量の輸血後,血色素が崩壊して,鉄を含む色素が沈着する),胆汁色素(黄疸)がある。
出典 株式会社平凡社世界大百科事典 第2版について 情報 |
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