Vaginal candidiasis

Japanese: 腟カンジダ症 - ちつカンジダしょう(英語表記)Vaginal candidiasis
Vaginal candidiasis

What is the disease?

In women of reproductive age, the ovaries are active and estrogen (female hormone) causes a large amount of glycogen-containing Vaginal epithelium ( Body condition ) Cells proliferate and differentiate.

Doderlein in the vagina Vaginal bacillus ( Chiropractic care ) A bacterium called (vaginal lactobacillus bacillus) is always present and breaks down this glycogen into lactic acid to keep the vagina acidic and prevent other bacteria from invading (self-cleaning effect). However, if this self-cleaning effect is broken down for some reason, various types of vaginitis and vulvitis will develop.

Vaginal candidiasis is a disease caused by the abnormal proliferation of the fungus Candida, which is also normally present in the vagina. The trigger is the bacterial growth of the vagina due to a decrease in pH in the vagina caused by increased estrogen secretion. plexus ( yes ) These include fluctuations in the serum albumin, diabetes, bacterial replacement due to antibiotic administration, pregnancy, and large doses of corticosteroids or immunosuppressants.

Possible routes of infection include sexual intercourse, feces, urine, hands, towels, etc.

Vaginal candidiasis is Vulvovaginal mycosis ( Good news for the newborn ) It is said that about 75% of women will experience vulvovaginal candidiasis at least once in their lifetime, and about 45% will experience it two or more times.

How symptoms manifest

On the vulva Itching ( Soybean paste ) (itch), Burning sensation ( Shakunetsu ) appears strongly. Porridge-like ( College ) , sake lees-like Leucorrhea ( Taige ) The vaginal discharge increases. Redness and swelling of the vulva are seen, and erythema or Small pustules ( Information ) It may also be accompanied by.

Candida infections can cause no symptoms, but treatment is usually given if symptoms are present.

Testing and diagnosis

The diagnosis is based on the above symptoms, findings in the vaginal discharge, and detection of bacteria. There are two ways to detect bacteria: directly observing the vaginal discharge under a microscope and detecting the bacteria (microscopic examination), or culturing the vaginal discharge. The detection rate is higher with the culture method than with the microscopic examination.

Treatment methods

Use vaginal tablets containing antifungal drugs and apply ointments or creams to the vulva at the same time. Use of steroid ointments is contraindicated. Generally, imidazole drugs (Adestan G300, Oxinazole V600, etc.) are used for about a week, and if the effect is insufficient, they are used for another week.

In cases where the condition is difficult to treat, the cause will be identified and oral medication may be administered. However, oral medication should not be used in pregnant women.

What to do if you notice an illness

If you experience any of the above symptoms, please visit an obstetrician-gynecologist. In addition, during pregnancy, treatment is provided from the 13th week onwards to prevent infection in the uterus and the birth canal.

Toshihiro Fujiwara

Source: Houken “Sixth Edition Family Medicine Encyclopedia” Information about the Sixth Edition Family Medicine Encyclopedia

Japanese:

どんな病気か

 生殖年齢にある女性では卵巣機能が活発で、エストロゲン(女性ホルモン)の作用により、多量のグリコーゲンを含んだ腟上皮(ちつじょうひ)細胞が増殖分化します。

 腟内にはデーデルライン腟桿菌(ちつかんきん)(腟乳酸菌桿菌)という菌が常在していて、このグリコーゲンを乳酸に分解して腟内を酸性に保ち、ほかの細菌の侵入を阻止しています(自浄作用)。しかし、何らかの原因により、この自浄作用が破綻した場合に、いろいろな腟炎、外陰炎が発症します。

 腟カンジダ症は、やはり腟に常在しているカンジダという真菌が異常増殖して発症する病気です。その誘因としては、エストロゲン分泌亢進による、腟内㏗の低下に伴う細菌(そう)の変動、糖尿病、抗生剤投与による菌交代現象、妊娠、副腎皮質ステロイド薬や免疫抑制薬の大量投与などがあげられます。

 感染経路は、性交、便や尿、手指やタオルなどが考えられます。

 腟カンジダ症は、外陰腟真菌症(がいいんちつしんきんしょう)の90%程度を占めます。75%ほどの女性は生涯に1回は、また45%ほどの女性は2回以上、外陰腟カンジダ症を経験するといわれています。

症状の現れ方

 外陰部に瘙痒感(そうようかん)(かゆみ)、灼熱感(しゃくねつかん)が強く現れます。粥状(じゅくじょう)、酒粕状の帯下(たいげ)(おりもの)が増加します。外陰部の発赤、はれがみられ、周辺に紅斑や小膿疱(しょうのうほう)を伴うこともあります。

 カンジダに感染していても症状のないこともあり、通常は症状がある場合に治療を行います。

検査と診断

 前記の症状と、帯下の所見、菌の検出により診断します。菌の検出には直接、帯下を顕微鏡で観察し、菌体を検出する方法(鏡検)と、帯下を培養する方法があります。培養法のほうが鏡検より検出率はよくなります。

治療の方法

 抗真菌薬配合の腟錠を使用し、同時に軟膏やクリームを外陰部に塗ります。ステロイド軟膏の使用は禁忌です。薬剤は一般的に、イミダゾール系(アデスタンG300、オキナゾールV600など)を1週間程度使用し、効果が不十分な場合は、さらに1週間使用します。

 難治性の場合は、原因の検索を行い、経口薬の投与も行うことがあります。ただし妊婦の場合、経口薬は使用しません。

病気に気づいたらどうする

 前記の症状が現れたら、産婦人科を受診してください。また、妊娠中は子宮内感染や産道感染の予防のため、妊娠13週以降から治療を行います。

藤原 敏博

出典 法研「六訂版 家庭医学大全科」六訂版 家庭医学大全科について 情報

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