Vitamin D deficiency seen in children (in adults, vitamin D deficiency manifests as osteomalacia). Rickets means hunchback, and this disease has been known since ancient times, but its pathology was not clear for a long time. In the 17th century, F. Grisson described rickets in detail. However, it was not until the 20th century that the true nature of rickets was revealed, and in 1919, E. Mellanby of England succeeded in experimentally inducing rickets in puppies, revealing that it was vitamin D deficiency. Source: Heibonsha World Encyclopedia, 2nd Edition Information |
小児にみられるビタミンD欠乏症(大人ではビタミンD欠乏は骨軟化症として現れる)。佝僂はせむしの意で,この病気は古くから知られていたが,その病態は長いこと明らかではなかった。17世紀にはF.グリッソンがくる病について詳細に記述している。しかし,くる病についての本態が明らかになったのは20世紀に入ってからで,1919年イギリスのメランビーE.Mellanbyが,子イヌに実験的にくる病を起こすことに成功したことによって,ビタミンD欠乏症であることが明らかになった。
出典 株式会社平凡社世界大百科事典 第2版について 情報 |
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