…(1)CRF is an abbreviation for corticotropin releasing factor, and is also known as ACTH secretion promoting factor or adrenocorticotropic hormone secretion promoting factor. In 1955, R. Guillemin et al. and AVSchally et al. each independently demonstrated the presence of CRF in the hypothalamus. However, attempts to purify it were unsuccessful for many years, and it was not until 1981 that CRF was finally isolated and identified, and its complete amino acid sequence was determined. … *Some of the terminology that mentions "Guillemin, R." is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…(1)CRF corticotropin releasing factorの略で,ACTH分泌促進因子,副腎皮質刺激ホルモン分泌促進因子ともいう。1955年,ギルミンR.GuilleminらとシャリーA.V.Schallyらは,それぞれ別個にCRFが視床下部に存在することを証明した。しかし,その後長期にわたってその精製の試みは成功せず,81年になって,ようやくCRFが分離同定され,その全アミノ酸配列が決定された。… ※「ギルミン,R.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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