Coronary insufficiency - kanfuzen

A general term for various pathological conditions that occur when the coronary arteries are unable to adequately supply the amount of blood required by the myocardium. Generally, it is often used synonymously with clinical disease names such as angina pectoris and myocardial infarction, but it is actually a term used as a pathophysiological concept of an imbalance between the myocardial oxygen demand and supply. Important pathological conditions that cause coronary insufficiency include coronary artery sclerosis, coronary artery thrombosis, and coronary artery spasm, but coronary insufficiency can also be caused by severe anemia in which the blood's oxygen-carrying capacity is significantly reduced, or by a relative oxygen deficiency in the myocardium due to increased myocardial oxygen consumption caused by significant cardiac hypertrophy.

[Michitoshi Inoue]

Source: Shogakukan Encyclopedia Nipponica About Encyclopedia Nipponica Information | Legend

心筋が必要とする血液量を冠状動脈が十分に供給できないためにおこる諸病態の総称。一般的には狭心症、心筋梗塞(こうそく)などの臨床的病名と同義的に用いられることが多いが、本来は心筋の酸素需要と供給の不均衡という病態生理学的な概念として使用される用語である。冠不全をきたす病態としては、冠状動脈硬化症、冠状動脈血栓症、冠状動脈攣縮(れんしゅく)が重要であるが、血液の酸素運搬能が著しく低下する重症の貧血、あるいは著しい心肥大による心筋酸素消費量の亢進(こうしん)に伴う心筋の相対的酸素不足などによっても冠不全がみられることもある。

［井上通敏］

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