[EC 2.3.2.2.]. Also known as γ-glutamyltransferase. An enzyme that catalyzes the reaction of cleaving the peptide bond at the γ position of γ-glutamyl compounds such as glutathione and transferring glutamic acid or a peptide with glutamic acid at the end to the N-terminus of another peptide. Glutathione is usually the substrate. It is found in the liver, kidneys, pancreas, etc. Blood levels increase significantly in cases of hepatitis, etc. Source: Asakura Publishing Nutrition and Biochemistry Dictionary Information |
[EC2.3.2.2.].γ-グルタミルトランスフェラーゼともいう.グルタチオンなどγ-グルタミル化合物のγ位のペプチド結合を切断して他のペプチドのN末端へグルタミン酸もしくはグルタミン酸を末端にもつペプチドを転移する反応を触媒する酵素.通常グルタチオンが基質である.肝臓,腎臓,膵臓などに存在.肝炎などで血中濃度が著増する.
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