Oxamycin - Oxamycin

Japanese: オキザマイシン - おきざまいしん
Oxamycin - Oxamycin

... Aminoglycoside antibiotics are not absorbed by oral administration, so they are administered by injection, but although the strength of the drugs varies, they have side effects such as hearing loss. In addition, antituberculous drugs are used in combination with other drugs to suppress the emergence of resistant bacteria and reduce side effects. In addition to synthetic drugs such as phenytoin and hydrazides, aminoglycosides and other antibiotics such as cycloserine (oxamycin) and rifampicin are used, making the problem of resistant tuberculosis bacteria less serious. (3) Chloramphenicol A broad-spectrum antibiotic discovered by P. Ehrlich in 1947, the emergence of chloramphenicol has made it possible to treat various diseases, including typhoid fever, which had previously been difficult to treat, and it has become widely used. ...

*Some of the terminology that mentions "oxamycin" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…アミノ配糖体抗生物質は,経口投与により吸収されないので注射で用いるが,強弱の差こそあれ聴力障害などの副作用を伴う。なお,抗結核薬としては,耐性菌の出現を抑え副作用を軽減する目的から,多剤併用を行うが,パス,ヒドラジドなどの合成剤に併せて,抗生物質としてアミノ配糖体のほかにサイクロセリン(オキザマイシン),リファンピシンなどが用いられ,耐性結核菌の問題もあまり深刻でなくなった。(3)クロラムフェニコール P.エールリヒにより1947年に発見された広範囲スペクトル抗生物質で,クロラムフェニコールの出現により,それまで治療困難だった腸チフスをはじめとする各種疾患の治療が可能となり,広く使われるようになった。…

※「オキザマイシン」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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