…It was with the discovery of secretin by WM Bayliss and EH Starling in 1902 that it became clear that the digestive tract not only digests and absorbs food, but also performs endocrine functions. Gastrin was discovered in 1905, and currently, in addition to the two mentioned above, other digestive hormones known include cholecystokinin-pancreozymin (CCK-PZ), GIP (gastric inhibitory polypeptide), VIP (vasoactive intestinal polypeptide), motilin, and somatostatin. Recently, it has been discovered that these digestive hormones are also present in the brain, and conversely, hormones found in the brain are also found in the digestive tract, so these hormones are sometimes called brain-gut peptides. … *Some of the terminology that refers to "gastric acid secretion inhibitory peptide" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…消化管が食物の消化・吸収のみならず,内分泌機能を営んでいることが明らかになったのは,1902年のベーリスW.M.BaylissとスターリングE.H.Starlingによるセクレチンの発見に始まる。ついで05年にガストリンが発見されたが,現在,消化管ホルモンとして上記の二つのほかにコレシストキニン‐パンクレオチミンcholecystokinin‐pancreozymin(CCK‐PZ),GIP(gastric inhibitory polypeptide,胃酸分泌抑制ペプチド),VIP(vasoactive intestinal polypeptide,血管作動性腸管ペプチド),モチリン,ソマトスタチンなどが知られている。最近では,これらの消化管ホルモンが脳内にも存在することがわかり,また逆に脳で発見されたホルモンが消化管にも存在することが判明したので,これらのホルモンは脳‐腸管ペプチドbrain‐gut peptideと呼ばれることもある。… ※「胃酸分泌抑制ペプチド」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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