…It inhibits DNA synthesis, but can cause bone marrow toxicity, cardiotoxicity, and hair loss. Aclarubicin (aclacinomycin) was developed as a drug with fewer side effects. It mainly inhibits RNA synthesis and has fewer side effects. … *Some of the terminology that mentions "aclacinomycin" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…DNA合成を阻害するが,骨髄毒性のほか,心臓毒性や脱毛が現れることがある。より副作用の少ないものとしてアクラルビシン(アクラシノマイシン)が開発された。これは主としてRNA合成を阻害し,副作用も少ない。… ※「アクラシノマイシン」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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