IgE antibody - IgE antibody

Japanese: IgE 抗体 - あいじーいーこうたい
IgE antibody - IgE antibody

…When the body comes into contact with a pathogenic antigen (through inhalation, oral ingestion, injection, etc.), the body begins to produce antibodies against it. Among these antibodies, the immunoglobulin Ig E antibody (also called reagin) has tissue adhesion properties and adheres to the surface of mast cells present in connective tissue. When the pathogenic antigen invades again, an antigen-antibody reaction occurs on the surface of the mast cells, resulting in the degranulation of the granules contained in the mast cells, releasing chemical messengers such as histamine, SRS-A (slow reactive substance of anaphylaxis), and ECF (eosinophile chemotactic factor) from the cells. …

From [Allergens]

…Allergies [Masaharu Muranaka]. . .

From [Bronchial Asthma]

...Aspirin asthma, in which attacks occur when taking antipyretics and analgesics, is seen in about 10% of bronchial asthma patients, but since attacks often progress rapidly to severe attacks, great care must be taken when taking medication.
[Diagnosis, Severity]
The diagnosis of bronchial asthma is based mainly on the above-mentioned symptoms and auscultation findings, but allergy tests such as serum IgE levels, blood eosinophil counts, allergen searches (skin reactions, specific IgE antibody measurements, histamine release tests, etc.), sputum tests, etc. are also used as references, and respiratory function tests and chest X-rays are also performed. The severity of bronchial asthma is divided into three stages: mild, moderate, and severe.

From [Parasite Allergy]

…Richard Benedict Goldschmidt (1910) was the first to recognize allergic symptoms caused by parasites, and wrote that some zoologists studying roundworms had conjunctivitis, headaches, swelling and pain in the fingers, severe coughing attacks, and asthma symptoms. The reasons why allergic reactions occur due to parasitic infection include the fact that the parasite's body or secretions contain antigenic substances that act as allergens, and that infection easily induces helper T cells that effectively and persistently promote the production of IgE antibodies. When IgE antibodies against parasites are produced, they bind to receptors on the cell membrane of mast cells (fat cells) in tissues and basophils in the blood. …

*Some of the terminology that mentions "IgE antibody" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…病因となる抗原に生体が触れると(吸入,経口,注射などの経路で),生体はそれに対して抗体を産生するようになる。これらの抗体のうち,免疫グロブリンであるIg E抗体(レアギンreaginともいう)は組織固着性があり,結合組織中に存在するマスト細胞の表面に固着する。そこに病因となる抗原が再び侵入してくると抗原抗体反応がマスト細胞の表面で起こり,その結果,マスト細胞に含まれている顆粒が脱顆粒現象を起こし,顆粒の中に含まれているヒスタミン,SRS‐A(slow reactive substance of anaphylaxis),ECF(eosinophile chemotactic factor)などの化学伝達物質を細胞外に遊離する。…

【アレルゲン】より

…アレルギー【村中 正治】。。…

【気管支喘息】より

…なかでも解熱鎮痛剤の服用により発作が出現するアスピリン喘息は,気管支喘息患者の約10%に見られるが,急速に重篤発作をきたす場合が多いため,薬の服用には十分な注意が必要である。
【診断,重症度】
気管支喘息の診断は,前述の症状の問診や聴診所見が中心となるが,アレルギー検査として血清IgE値,血中好酸球数,アレルゲン検索(皮膚反応や特異的IgE抗体測定,ヒスタミン遊離試験など),喀痰検査などが参考となり,また呼吸機能検査や胸部レントゲン撮影なども行われる。 気管支喘息の重症度は,軽症,中等症,重症の3段階に分けられる。…

【寄生虫アレルギー】より

…寄生虫によるアレルギー症状をはじめて認めたのはゴルトシュミットRichard Benedict Goldschmidt(1910)で,ウマカイチュウの研究をしている動物学者の中に結膜炎,頭痛,手指の腫張や痛み,激しい咳発作や喘息(ぜんそく)症状を示す者があることを記載している。寄生虫感染によってアレルギー反応が起こる理由としては,寄生虫の虫体あるいは分泌排出物中にアレルゲンとなる抗原物質が含まれていること,感染によってIgE抗体の産生を効果的かつ持続的に促すヘルパーT細胞が容易に誘導されてくることなどが挙げられる。寄生虫に対するIgE抗体が産生されると,それは組織内のマスト細胞(肥満細胞)や血液中の好塩基球の細胞膜上のレセプターに結合する。…

※「IgE 抗体」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

<<:  ICA (Cooperative Association)

>>:  ICEF-JAF - ICEF-JAF

Recommend

British Library

…Due to the expansion of the collections and the ...

Hino Sukena

Year of death: May 2, 1338 (May 21) Year of birth:...

Toyo Bunko - Toyo Bunko

This is a library and research institute that col...

The Documents of Iriki

…He later lectured on Japanese history and Europe...

Ouch - It hurts

...Its English name is rabbit fish because it loo...

Calvinism - Calvinism

Protestantism is a philosophy that developed from...

Fishermen - gyogyōjūjisha

…(1) The complexity of the union's membership...

Non-human

〘Noun〙① Buddhist term. Meaning not human, a demon ...

Pastorale (English spelling)

…Symphony composed by Beethoven. This Symphony No...

ε-neighborhood

...Here, d ( x , a ) is the distance between x an...

Brake van - Air vehicle

The term "kankyu ressha" (express train)...

Numata [city] - Numata

A city in northern Gunma Prefecture. It was incorp...

Sonic wave height meter - Onpahakokei

…An experiment covering an area of ​​300 square k...

Manaus (English spelling)

Manáos (until 1939). Capital of Amazonas State, no...