…By using cell lines that can be subcultured and have stable properties, or cloned cells derived from a single cell, it is possible to conduct research on genetically uniform cells. Monolayer culture is when cells adhere to the bottom of the culture vessel and grow by stretching out their cytoplasm. Most normal cells, except for mature hematopoietic cells, grow in this manner. Normal cells grow and cover the bottom of the culture vessel, and when they come into contact with each other, they exhibit contact inhibition, which prevents them from dividing any further. … *Some of the terminology that refers to "monolayer culture" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…継代培養が可能で性状の安定な細胞株や,単一細胞に由来するクローン細胞を用いると,遺伝的に均一な細胞での研究が可能である。細胞が培養器内で底面に接着し,細胞質をのばして増殖するのが単層培養monolayer cultureで,成熟した造血細胞以外の大部分の正常細胞はこの形式で増殖する。正常な細胞は,増殖して培養器底面をおおいつくし,互いに接触するようになると接触阻止現象contact inhibitionを生じて,それ以上は分裂しなくなる性質をもっている。… ※「monolayer culture」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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