...Its physiological importance has been noted due to its wide distribution, but its significance was not fully understood in birds and mammals because it is biosynthesized from γ-aminobutyric acid. Since its identification as an essential growth factor for the mealworm by G. Fraenkel and others (1947), its function in the body has become clear. Mitochondria isolated from liver and other sources do not oxidize fatty acids unless a catalytic amount of carnitine is added. ... *Some of the terminology that mentions "Fraenkel, G." is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…広範な分布からその生理的重要性が注目されてきたが,鳥類,哺乳類ではγ‐アミノ酪酸から生合成されるためにその意義がなかなか理解されなかった。フレンケルG.Fraenkelらによってコメゴミムシダマシの必須成長因子として同定されて(1947)以来その生体内での機能がわかってきた。肝臓などから単離したミトコンドリアは触媒量のカルニチンを加えないと脂肪酸が酸化されない。… ※「Fraenkel,G.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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