…Granulation tissue is composed mainly of newly formed capillaries and fibroblasts with contractile capacity, with the addition of inflammatory cell infiltration. When the filling of the defect with granulation tissue is complete and the inflammatory reaction subsides, the secretion of collagen fibers from the fibroblasts becomes active, the number of blood vessels decreases, the water content decreases, the granulation tissue shrinks, and scars (fibrosis) form (this phenomenon is the cause of wound contraction). The collagen fibers are also gradually absorbed. … *Some of the terminology that mentions "fibrosis" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…肉芽組織の構成は,新生毛細血管と,収縮能をもつ繊維芽細胞が主体であり,これに炎症性の細胞浸潤が加わったものである。肉芽組織による欠損部の充てんが完了し,炎症反応が消退すると,繊維芽細胞からの膠原(こうげん)繊維の分泌が活発になり,血管の数が少なくなって,水分が減少して,肉芽は収縮し,瘢痕(はんこん)化(繊維化fibrosis)する(創のひきつれはこの現象による)。膠原繊維もしだいに吸収される。… ※「fibrosis」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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