…The secretion method in which secretions escape without damaging the cell body when observed under an optical microscope has been collectively called leaky secretion (eccrine secretion). However, observation under an electron microscope has led to the classification of leaky secretion into exocytosis and diacrine secretion. Exocytosis is mainly seen in cells that secrete peptides and proteins, and is a type in which secretory granules covering the limiting membrane approach the cell surface, then the limiting membrane and cell membrane fuse, the fusion point opens, and the granule contents escape. … From [Gland]...It is known that the release of secretory granules by exocytosis is triggered by the entry of calcium ions into the cell, and that microtubules and filaments are involved in the movement of the granules through the cytoplasm toward the cell membrane during the release of secretory granules. (b) Diacrine secretion This refers to the secretion of a substance that passes through the cell membrane without changing it at all. The substance that is excreted in this way must be a low molecular weight substance that can pass through the cell membrane. ... *Some of the terminology that mentions "diacrine secretion" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…光学顕微鏡によって観察した場合に分泌物が細胞体を傷つけずに外へ出る分泌方式を総称して漏出分泌(エクリン分泌eccrine secretion)と呼んできた。しかし,電子顕微鏡での観察によって,漏出分泌は開口分泌exocytosisと透出分泌diacrine secretionに分けられるようになった。開口分泌はおもにペプチドやタンパク質を分泌する細胞にみられ,限界膜を覆った分泌顆粒が細胞の表面に近づき,ついで限界膜と細胞膜が癒合し,癒合点が開口し,顆粒内容物が外へ出る様式である。… 【腺】より…開口分泌による分泌顆粒の放出が,細胞内にカルシウムイオンの侵入することによりひき起こされること,また分泌顆粒の放出にさいして,顆粒が細胞質内を細胞膜に向かって移動するのに微小管やフィラメントが関与することが知られている。(b)透出分泌diacrine secretion 分泌物が細胞膜をまったく変化させずに,細胞膜を通過して外へしみ出るものをいう。このようにして排出される物質は,細胞膜を通過しうる低分子のものでなければならない。… ※「diacrine secretion」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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