…It was discovered in 1905 by J.S.Edkins of England, and in 1964 its structural formula was determined by R.A.Gregory and H.J.Tracy of the United States as a polypeptide consisting of 17 amino acids. It was later discovered that the majority of gastrinos in the blood consist of 34 amino acids, and the 17-amino acid form is called little gastrin, and the 34-amino acid form is called big gastrin. In both cases, the active center is a four-amino acid bond at the C-terminus. … *Some of the terminology that mentions "big gastrin" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…1905年イギリスのエドキンズJ.S.Edkinsにより発見され,64年アメリカのグレゴリーR.A.GregoryとトレーシーH.J.Tracyによりアミノ酸17個から成るポリペプチドとして構造式が決定された。その後,血液中ではアミノ酸34個のものが多いことがわかり,17個のものは小ガストリンlittle gastrin,34個のものは大ガストリンbig gastrinとよばれている。いずれも活性中心はC末端の4個のアミノ酸結合である。… ※「big gastrin」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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