…In 1896, Oliver G. Oliver and Schäfer EASchäfer of England extracted a blood pressure-increasing substance from the adrenal gland, which Ebel J.A. Bel isolated as a benzoyl compound and named it epinephrine. In 1901, Takamine Jokichi and Aldrich TB Aldrich succeeded in crystallizing it, and Takamine named it adrenaline (the patent name at the time). In 1904, Stolz F. succeeded in synthesizing racemic dl -adrenaline, and in 1908, Flächer succeeded in separating the two optical isomers, d- and l- . … *Some of the terminology that refers to "Aldrich, TB" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…1896年,イギリスのオリバーG.OliverとシェーファーE.A.Schäferらは副腎から血圧上昇物質を抽出,これをエーベルJ.J.Abelがベンゾイル化合物として単離し,エピネフリンと命名した。1901年,高峰譲吉とアルドリヒT.B.Aldrichが相前後して結晶化に成功,高峰はこれをアドレナリン(当時,特許名)と命名した。さらに04年,シュトルツF.Stolzがラセミ体のdl‐アドレナリンの合成に成功し,08年,フレッヘルFlächerがd‐体とl‐体の二つの光学異性体の分離に成功した。… ※「Aldrich,T.B.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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