WDHA syndrome
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The main symptoms of this disease are watery diarrhea, hypokalemia, and achlorhydria, and the name is an acronym of these three symptoms. It occurs when a pancreatic tumor produces a substance called VIP (short for vasoactive intestinal polypeptide). Like gastrin, VIP is a gastrointestinal hormone, and this syndrome, along with Zollinger-Ellison syndrome, is considered a gastrointestinal hormone-producing tumor. Source: Heibonsha World Encyclopedia, 2nd Edition Information |
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水様性下痢watery diarrhea，低カリウム血症hypokalemia，無酸症achlorhydriaをおもな症状とする病気で，それらの頭文字をとって名づけられた。膵臓の腫瘍がVIP(vasoactive intestinal polypeptideの略)とよばれる物質を産生することによって起こる。VIPはガストリンと同じく消化管ホルモンの一つであり，本症候群はゾリンジャー=エリソン症候群と並んで消化管ホルモン産生腫瘍とよばれている。
出典 株式会社平凡社世界大百科事典 第２版について 情報 |
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