...Cells that have undergone necrosis swell, staining changes, and the striations disappear in striated muscle cells. Caseation necrosis seen in granulomas of tuberculosis is a type of coagulation necrosis, but it is said to become creamy due to the lipids in the bacterial components. [Yamaguchi Kazutoshi]... From [Cutaneous tuberculosis]…Those that develop at the site of BCG vaccination are caused by the bacteria entering the local area directly, but in other cases, the tuberculosis bacteria that entered the body, such as the lungs, reach the skin through the blood and cause lesions. Pathologically, it is characterized by the formation of tuberculous granulations and the accumulation of epithelioid cells and Langhans giant cells surrounding caseous necrosis (a state in which tissue dies and becomes cheese-like). It is broadly divided into true cutaneous tuberculosis and tuberculous rash. … *Some of the terminology explanations that mention "caseation necrosis" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…壊死に陥った細胞は腫大し,染色性が変化したり,横紋筋細胞では横紋が消失したりする。結核症の肉芽腫にみられる乾酪壊死は凝固壊死の一種であるが,菌体成分の脂質のためクリーム状になるとされている。【山口 和克】。… 【皮膚結核】より…BCG接種部位に生じるものは直接局所に菌が入ったために起こるものだが,それ以外はいったん肺など体内に入った結核菌が血液を通して皮膚に達して病変を生じたものである。病理学的には,結核性肉芽をつくり,乾酪壊死(組織が壊死してチーズ状になった状態)をかこんで類上皮細胞,ラングハンス巨細胞などが集合するのが特徴である。大きく真正皮膚結核と結核疹とに分けられる。… ※「乾酪壊死」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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