…Japan was the first country in the world to use experimental animal tumors to search for anticancer antibiotics, and it can be said that Japan is at the forefront of the world in this field. Antibiotics discovered in Japan and used clinically include Toju Hata's carzinophilin (1954), mitomycin (1956), Hamao Umezawa's bleomycin (1966), peplomycin (1977), aclacinomycin A (brand name Aclarubicin, 1977), Sueo Tateoka's chromomycin A 3 (1955), and Naosuke Ishida's neocarzinostatin (1965). Bleomycin and mitomycin in particular are also widely used overseas. Antibiotics discovered overseas that are used for treatment include actinomycin D, daunorubicin (brand name Daunomycin), and doxorubicin (brand name Adriamycin). … *Some of the terminology explanations that mention "carcinophilin" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…日本では,世界にさきがけて実験動物腫瘍を用いて制癌抗生物質の探索を始め,この分野では世界の水準の先端にあるといえる。日本で発見され臨床的に用いられているものに,秦藤樹のカルチノフィリン(1954),マイトマイシン(1956),梅沢浜夫のブレオマイシン(1966),ペプロマイシン(1977),アクラシノマイシンA(商品名アクラルビシン,1977),立岡末雄のクロモマイシンA3(1955),石田名香雄のネオカルチノスタチン(1965)があり,とくにブレオマイシン,マイトマイシンは外国でもよく用いられている。外国で発見されたもので治療に用いられているものに,アクチノマイシンD,ダウノルビシン(商品名ダウノマイシン),ドキソルビシン(商品名アドリアシン)がある。… ※「カルチノフィリン」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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