...A disease caused by a tumor (gastrinoma) of cells that produce gastrin, which occurs in the pancreas or the stomach/duodenal wall. It was named after the American surgeons RM Zollinger and EH Ellison, who first reported a case in 1955. It is characterized by hypergastrinemia, increased gastric acid secretion, and intractable peptic ulcers, which cause symptoms such as lower back pain, diarrhea, hematemesis, and bloody stool. *Some of the terminology that mentions "Ellison, EH" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…膵臓や胃・十二指腸壁に発生したガストリンを産生する細胞の腫瘍(ガストリノーマ)によって起こる疾患。1955年にアメリカの外科医ゾリンジャーR.M.ZollingerとエリソンE.H.Ellisonが初めて症例を報告したのでこの名がつけられた。高ガストリン血症,胃酸分泌亢進,難治性の消化性潰瘍がみられるのが特徴で,そのために腰痛,下痢,吐血,下血などの症状を呈する。… ※「エリソン,E.H.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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