…Epinephrine, also known as epinephrine, is one of the catecholamines, which are amines produced from aromatic amino acids. In 1896, Oliver G. Oliver and Schäfer EA Schäfer of England extracted a blood pressure-increasing substance from the adrenal glands, which Ebel J. Abel isolated as a benzoyl compound and named epinephrine. In 1901, Takamine Jokichi and Aldrich TB Aldrich succeeded in crystallizing it, and Takamine named it adrenaline (the patent name at the time). … From [Insulin]Insulin was discovered in 1921 by F. G. Banting and CH. Best in pancreatic extracts as a hypoglycemic substance. In 1926, J. Abel succeeded in crystallizing it, and in 1955, F. Sanger revealed its amino acid sequence. Insulin was the first protein whose amino acid sequence was determined. *Some of the terminology that refers to "Ebel, JJ" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…エピネフリンepinephrineとも呼ばれ,芳香族アミノ酸から生成されるアミン類であるカテコールアミンcatecholamineの一つ。1896年,イギリスのオリバーG.OliverとシェーファーE.A.Schäferらは副腎から血圧上昇物質を抽出,これをエーベルJ.J.Abelがベンゾイル化合物として単離し,エピネフリンと命名した。1901年,高峰譲吉とアルドリヒT.B.Aldrichが相前後して結晶化に成功,高峰はこれをアドレナリン(当時,特許名)と命名した。… 【インシュリン】より… インシュリンは1921年,バンティングF.G.BantingとベストC.H.Bestによって,膵臓の抽出物中から,血糖降下物質として見いだされた。次いで26年,エーベルJ.J.Abelが結晶化に成功,55年にサンガーF.Sangerがそのアミノ酸配列を明らかにした。インシュリンは,アミノ酸配列が決定された最初のタンパク質である。… ※「エーベル,J.J.」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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