Acetylsalicylic acid

Japanese: アセチルサリチル酸
Acetylsalicylic acid
C9H8O4 ( mw180.16) .

Also known as aspirin. A drug that is widely used as an antipyretic and anti-inflammatory agent, it acts by acetylating cyclooxygenase, an enzyme in the prostaglandin biosynthesis pathway, thereby inactivating it (acting as a cyclooxygenase inhibitor), and this is thought to be the reason for its efficacy. It also inhibits platelet aggregation, and is used to prevent blood clot formation.

Source: Asakura Publishing Nutrition and Biochemistry Dictionary Information

Japanese:
C9H8O4 (mw180.16).

 アスピリンともいう.解熱剤,抗炎症剤として広く用いられている薬品で,プロスタグランジン生合成経路の酵素であるシクロオキシゲナーゼをアセチル化して活性を失わせる作用(シクロオキシゲナーゼ阻害剤としての作用)があり,薬効はこれによるとされている.血小板凝集阻害作用もあり,血栓生成阻止の目的にも使われる.

出典 朝倉書店栄養・生化学辞典について 情報

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