Nuclear polyhedrosis - nuclear polyhedrosis

Japanese: 核多角体病 - かくたかくたいびょう（英語表記）nuclear polyhedrosis

This is one of a group of viral diseases of insects, which mainly occur in lepidopteran insects such as silkworms. The pathogenic virus is a rod-shaped particle 250-350 nm long and 40-60 nm wide, and the particles are usually bundled together and enveloped in a common outer membrane. The nucleic acid is double-stranded DNA. It invades many tissues such as blood cells, tracheal membrane, adipose tissue, and dermis, and proliferates in the cell nucleus, eventually forming proteinaceous inclusion bodies (2-4 μm in diameter) called polyhedra, in which many viruses become embedded. At the final stage of infection, tissues collapse and polyhedra are released into the blood, causing the blood to turn milky white and pus-like.

Source: Heibonsha World Encyclopedia, 2nd Edition Information

Japanese:

昆虫のウイルス病群の一つで，カイコなど主に鱗翅目昆虫に発生する。病原ウイルスは長さ250～350nm，幅40～60nmの杆（かん）状粒子で，通常粒子は束になって共通の外膜に包まれている。核酸は複鎖DNAである。血球，気管皮膜，脂肪組織，真皮など多くの組織を侵し，細胞核で増殖し，最終的に多角体といわれるタンパク性の封入体(直径2～4μm)を形成して多くのウイルスはその中に埋めこまれる。感染末期には組織が崩壊し，多角体が血液中に遊離する結果，血液は乳白色の膿汁状になる。

出典　株式会社平凡社世界大百科事典第２版について　情報

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