…the codon and anticodon bind in the opposite direction. The specificity of the bond between the third base of the codon and the first base of the anticodon is not high, and the wobble hypothesis explains the flexibility of the third base of the codon. On the ribosome particle, with the cooperation of mRNA, tRNA, and various factors, tRNA binds and arranges according to the codon of the mRNA molecule, amino acids attached to one end of the tRNA are linked together by peptide bonds, and finally, when the end-of-reading signal arrives, the synthesized polypeptide (protein) leaves the ribosome particle. … *Some explanations of terms that mention the "wobble hypothesis" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…コドンとアンチコドンは逆向きに結合する。コドンの3番目とアンチコドンの1番目の結合の特異性は高くなく,〈よろめき仮説wobble hypothesis〉は,コドンの3番目の塩基の自由度を説明している。リボソーム粒子上で,mRNA,tRNA,種々の因子の協同のもとに,mRNA分子のコドンに従ってtRNAが結合,配列し,tRNAの一端に結合するアミノ酸がペプチド結合によってつなぎあわされ,最後に読み終りの信号がくると,合成されたポリペプチド(タンパク質)はリボソーム粒子から離れていく。… ※「wobble hypothesis」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
>>: Wobbermin, EG (English spelling)
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