...These cytoskeletal structures can be identified by a fluorescence microscope by staining cells with fluorescent antibodies prepared using the respective constituent proteins as antigens. (1) Microtubules These hollow fibrous structures are the thickest in the cytoskeleton, measuring 250 nm, and are formed by polymerization of tubulin α and β, the main microtubule proteins. In addition, small amounts of proteins such as τ protein and microtubule-associated proteins (MAPs), which are necessary for the polymerization of microtubules and interactions with other fibrous structures, are added to this structure. ... From [Tubulin]...proteins that make up microtubules. Microtubules are tubular filamentous structures with a diameter of 24 nm that are found in almost all cells in the living world and are deeply involved in many physiological phenomena such as flagellar and ciliary movement, formation and maintenance of cell morphology, cell division, and transport within nerve axons. *Some of the terminology that mentions "microtubule" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…これらの繊維構造は,それぞれの構成タンパク質を抗原として調製した蛍光抗体で,細胞を染めれば,蛍光顕微鏡によってこれらの細胞骨格構造を識別することができる。(1)微小管microtubule 細胞骨格の中で最も太い250nmの中空の繊維構造で,おもな微小管タンパク質としてチューブリンα,βが重合してできたものである。そのほかに,微小管の重合や他の繊維構造との間の相互作用に必要なτタンパク質や微小管結合タンパク質(MAP)など少量のタンパク質がこの構造に加わっている。… 【チューブリン】より…微小管microtubuleを構成するタンパク質。微小管は生物界のほとんどすべての細胞に見いだされる直径24nmの管状繊維構造で,鞭毛・繊毛運動,細胞形態の形成・維持,細胞分裂,神経軸索内輸送などの多くの生理現象に深く関与している。… ※「microtubule」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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