…(1) Abnormality in the number of chromosomes In humans, aneuploidy is the most common, and is thought to occur due to non-disjunction of chromosomes during meiosis. In other words, if a chromosome does not separate, it can result in monosomy (where there should be two) or trisomy (where there should be three), resulting in an increase or decrease in the number of chromosomes. However, there are relatively few cases of monosomy because it makes survival difficult, and trisomy is the most commonly known type of aneuploidy. … *Some terminology explanations that mention "monosomy" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…(1)染色体数の異常 ヒトの場合,最もよくみられるのは異数体で,減数分裂に際しての染色体不分離によって起こると考えられている。すなわち,ある染色体が分離しなかったことにより,2個あるべき相同染色体が一つしかないモノソミーmonosomyになったり,3個になるトリソミーtrisomyになり,染色体数に増減が起こる。ただし,モノソミーの場合は生存が困難になるところから比較的例が少なく,異数体としてよく知られているものにはトリソミーが多い。… ※「monosomy」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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