...In oxidative enzymes that contain flavins, the substrate first reduces the flavin through a dehydrogenation reaction, and then the reduced flavin reacts with O 2 to produce H 2 O 2. Some enzymes catalyze reactions that incorporate oxygen atoms into the substrate as a result of direct reactions with molecular oxygen; these are called oxygenases. There are dioxygenases that catalyze reactions in which both O atoms in an oxygen molecule are incorporated into the substrate, and monooxygenases (also called hydroxylases) that incorporate one atom into the substrate and reduce the other to H 2 O; many of these enzymes contain metals such as iron and copper. ... *Some terminology explanations that mention "oxygenase" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…フラビンを含む酸化酵素では,脱水素反応によって基質がまずフラビンを還元し,ついで還元型フラビンがO2と反応して,H2O2を生ずる。 分子状酸素との直接反応の結果,酸素原子を基質にとりこむ様式の反応を触媒する酵素もあり,これらは酸素添加酵素(オキシゲナーゼoxygenase)と呼ばれる。酸素分子中の2原子のOがいずれも基質にとりこまれる反応を触媒するもの(ジオキシゲナーゼ)と,一方を基質にとりこみ,一方を還元してH2Oにするモノオキシゲナーゼ(ヒドロキシラーゼhydroxylaseともいう)とがあり,鉄,銅などの金属を含むものが多い。… ※「oxygenase」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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