...(2) There is a base sequence that regulates the expression of a protein on the 5' end side of the base sequence that corresponds to the amino acid sequence. (3) Transcription enzyme (RNA polymerase) recognizes a region of the regulatory region called a promoter, and synthesizes mRNA with a base sequence that corresponds to the DNA from the 5' end to the 3' end at a certain point downstream (on the 3' end side). (4) However, in order for transcription to occur, a cap protein must also be bound to the promoter region of the DNA, and a protein called a repressor must not be bound to the operator region. ... *Some terminology explanations that mention "promoter" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…(2)タンパク質のアミノ酸配列に対応する塩基配列より5′末端側に,その発現を調節する塩基配列がある。(3)転写酵素(RNAポリメラーゼ)は,調節部位のうちプロモーターpromoterと呼ばれる部位を認識し,その下流(3′末端側)のある地点より,DNAと対応する塩基配列をもつmRNAを5′末端から3′末端の向きに合成する。(4)しかし転写が行われるためには,ほかにDNAのプロモーター部位にキャップ(CAP)タンパク質が結合しており,オペレーター部位にリプレッサーrepressorというタンパク質が結合していないことが条件である。… ※「promoter」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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