Growth hormone release inhibiting factor

Japanese: growth hormone release inhibiting factor（英語表記）growthhormonereleaseinhibitingfactor

...H-Thr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH ₂ GRF has a growth hormone secretion promoting effect. (3) Somatostatin It is also called GIF (short for growth hormone release inhibiting factor) or SRIF (short for somatotropin release inhibiting factor). In 1973, Guillemin et al. discovered a fraction from sheep hypothalamic tissue that inhibited the secretion of growth hormone, purified it, and determined the structure of somatostatin, which is made up of 14 amino acids.

*Some of the terminology that refers to "growth hormone release inhibiting factor" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…H－Thr－Ala－Asp－Ala－Ile－Phe－Thr－Asn－Ser－Tyr－Arg－Lys－Val－Leu－Gly－Gln－Leu－Ser－Ala－Arg－Lys－Leu－Leu－Gln－Asp－Ile－Met－Ser－Arg－Gln－Gln－Gly－Glu－Ser－Asn－Gln－Glu－Arg－Gly－Ala－Arg－Ala－Arg－Leu－NH₂GRFは成長ホルモン分泌促進作用をもつ。(3)ソマトスタチンsomatostatin　成長ホルモン分泌抑制因子GIF(growth hormone release inhibiting factorの略)あるいはSRIF(somatolropin release inhibiting factorの略)ともいう。1973年，ギルミンらは，ヒツジの視床下部組織から成長ホルモンの分泌を抑制する分画を発見し，純化を行って14個のアミノ酸からなるソマトスタチンの構造を決定した。…

※「growth hormone release inhibiting factor」について言及している用語解説の一部を掲載しています。

出典｜株式会社平凡社世界大百科事典第２版について | 情報

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