Hemoglobinuria

Japanese: 血色素尿症 - けっしきそにょうしょう（英語表記）hemoglobinuria

A condition in which hemoglobin (blood pigment) is mixed in the urine. When red blood cells are destroyed in the bloodstream (hemolysis), hemoglobin is released into the blood, which then passes through the glomeruli of the kidneys and is released into the urine. The condition in which red blood cells are mixed in the urine is called "hematuria," but this is different from hemoglobinuria. In hemoglobinuria, the urine often appears brown to dark brown. It is seen in hemolytic anemias such as paroxysmal nocturnal hemoglobinuria, paroxysmal cold hemoglobinuria, cold agglutinin disease, glucose-6-phosphate dehydrogenase deficiency, red blood cell fragmentation syndrome, and in diseases such as malaria and sepsis.

Source: Heibonsha World Encyclopedia, 2nd Edition Information

Japanese:

尿にヘモグロビン(血色素)が混じっている状態。血管内で赤血球の破壊(溶血)があって血中にヘモグロビンが遊離し，これが腎臓の糸球体を通過して尿中に出てくるものである。尿に赤血球が混じっている状態を〈血尿〉というが，これと血色素尿とは異なる。血色素尿では尿の色が茶～黒褐色を呈することが多い。溶血性貧血のうち発作性夜間血色素尿症，発作性寒冷血色素尿症，寒冷凝集素病，グルコース‐6‐リン酸脱水素酵素欠乏症，赤血球破砕症候群，あるいはマラリアや敗血症などの病気のときに見られる。

出典　株式会社平凡社世界大百科事典第２版について　情報

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