...Although the mechanism of cell necrosis remains largely unknown, it is closely related to the loss of ATP in the membrane system and the influx of calcium ions into the cells. In cells that have fallen into necrosis, protein coagulation begins, the cells harden, and the cell nucleus collapses and disappears (this is called coagulation necrosis). In addition, hydrolases in lysosomes are activated, causing autolysis. ... *Some of the terminology explanations that mention "coagulative necrosis" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…細胞壊死のメカニズムには不明の点が多いが,膜系のATPの喪失,カルシウムイオンの細胞内流入が密に関係している。壊死に陥った細胞ではタンパク質凝固がはじまり,硬化し,細胞核が崩壊し,消失する(これを凝固壊死coagulation necrosisという)。またリソソームの加水分解酵素が活性化され自己融解がおこる。… ※「凝固壊死」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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