L-Asparaginase

Japanese: L‐アスパラギナーゼ - えるあすぱらぎなーぜ
L-Asparaginase

...Since male or female hormone preparations often have side effects such as masculinization or feminization when used alone, drugs with fewer side effects, such as tamoxifen (Nolvadex) and mepitiostane (Thioderm), have recently been developed and are used in the treatment of breast cancer.
[Other anticancer drugs]
Drugs that do not fall into the above categories include procarbazine (Naturan), cisplatin (Randa or Briplatin), L-asparaginase (Leunase), and estramustine (Estracyt), which are used to treat malignant lymphoma, various solid cancers, leukemia, and prostate cancer, respectively. Of these, cisplatin is a platinum complex compound that was discovered in the United States in the late 1960s and was recently introduced to Japan.

*Some of the terminology that mentions "L-asparaginase" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…男性または女性ホルモン製剤そのままでは男性化ないし女性化の副作用が現れることが多いため,それらの副作用の少ない薬剤として乳癌治療にタモキシフェン(ノルバデックス)やメピチオスタン(チオデロン)が最近開発され,用いられている。
[その他の制癌薬]
 以上の分類に属さないものにプロカルバジン(ナツラン),シスプラチン(ランダまたはブリプラチン),L‐アスパラギナーゼ(ロイナーゼ),エストラムスチン(エストラサイト)などがあり,それぞれ悪性リンパ腫,種々の固形癌,白血病,前立腺癌の治療に利用されている。このうちシスプラチンは白金の錯化合物で,1960年代後半にアメリカで発見され最近日本に導入された。…

※「L‐アスパラギナーゼ」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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