…When two or more antibody molecules react with an antigen, the stimulation is transmitted to the cell, causing the cell to degranulate and release histamine and other chemical mediators. These substances cause increased vascular permeability, smooth muscle contraction, an increase in the number of eosinophils and their migration to the local area, resulting in the so-called Type I allergy symptoms. The table below lists some typical symptoms caused by parasitic infections. The presence of IgE antibodies can be demonstrated by immediate intradermal reactions, Prausnitz-Küstner reactions, and RAST (short for radioallergosorbent test). … *Some of the terminology that refers to "Type I allergy" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…そして2分子以上の抗体が抗原と反応すると,その刺激が細胞内に伝えられ,細胞は脱顆粒現象を起こしてヒスタミンその他の化学伝達物質を放出する。これらの物質によって,血管透過性の亢進,平滑筋の収縮,好酸球数の増加・局所への遊走などが起こり,いわゆるI型アレルギーの症状が発現するのであるが,寄生虫感染によるその代表的なものを挙げると表のようになる。なお,IgE抗体の存在は,即時型皮内反応,プラウスニッツ=キュストナー反応Prausnitz‐Küstner reaction,RAST(radioallergosorbent testの略)などによって証明することができる。… ※「I 型アレルギー」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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