… Organ damage caused by iron deposition can affect the entire body, including the liver, pancreas, spleen, kidneys, digestive tract, endocrine glands, cardiac muscle, skeletal muscles, joints, and bone marrow, but diabetes and its complications are often the first symptoms. In addition to symptoms such as general fatigue, dry mouth, and weight loss, the skin takes on a bronze color due to melanin pigmentation, so this disease has also been called bronze diabetes. Diagnosis is made by clinical findings and by liver biopsy to confirm large amounts of iron deposition in liver cells. … *Some of the terminology that refers to "bronze diabetes" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…鉄沈着による臓器障害は,肝臓,膵臓,脾臓,腎臓,消化管,内分泌腺,心筋,骨格筋,関節,骨髄と全身に及ぶが,糖尿病とその合併症が初めの症状となるものが多い。全身倦怠,口渇,体重減少などの症状に加えて,皮膚はメラニン色素沈着により青銅(ブロンズ)色を呈するため,この病気に対しブロンズ糖尿bronze diabetesという別名も使われたことがある。診断は,臨床所見と,肝生検によって肝細胞内の多量の鉄沈着を確認することにより行われる。… ※「bronze diabetes」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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