…Methods that use cardiolipin, a lipid from cow's heart, as an antigen (also called lipid antigen method, STS) include the glass plate method, RPR method, agglutination method, and other methods, while methods that use Treponema pallidum as an antigen include the TPHA method and FTA-ABS method. The cardiolipin antigen method may show a positive result in cases other than syphilis infection, such as collagen diseases such as systemic lupus erythematosus, and viral infections such as chickenpox and measles, which is a so-called biological false positive (BFP). However, the TPHA method and FTA-ABS method show a negative result, which can be distinguished from the positive serum reaction that occurs in syphilis infection. … *Some explanations of terms that refer to "biological false positive" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…牛の心臓の脂質であるカルジオリピンを抗原とする方法(脂質抗原法,STSともいう)にはガラス板法,RPR法,凝集法,緒方法など,梅毒トレポネマを抗原とする方法にはTPHA法,FTA‐ABS法がある。カルジオリピン抗原法では梅毒感染以外の場合,すなわち全身性エリテマトーデスなど膠原(こうげん)病や水痘,麻疹などのウイルス感染症などのさいは陽性となる,いわゆる生物学的偽陽性biological false positive(BFP)を示すことがある。しかしTPHA法やFTA‐ABS法では陰性となるので,梅毒感染のさいに陽性となる血清反応と区別できる。… ※「biological false positive」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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