This drug makes people dislike alcohol, and is also called an alcohol aversion drug. If this drug is administered beforehand, the patient's reaction to alcohol becomes abnormal, causing them to suffer from unpleasant symptoms, strengthening the chronic alcoholic's desire to quit drinking. One example is disulfiram (brand name Antabous). A Danish doctor was researching the effectiveness of disulfiram as an anthelmintic when he took it and attended a cocktail party, where he developed severe symptoms of alcohol poisoning, and discovered that it works as a withdrawal drug. Source: Heibonsha World Encyclopedia, 2nd Edition Information |
酒を嫌いにさせる薬で,嫌酒薬ともいう。この薬をあらかじめ投与しておくと,アルコールに対する反応が異常になって不快な症状に苦しむため,慢性アルコール中毒患者が酒をやめたいと望む気持ちを強化してくれる。ジスルフィラムdisulfiram(商品名アンタブース)がある。デンマークの医師がジスルフィラムの駆虫薬としての効果を研究中,それを内服してカクテルパーティに出席し,アルコールで激しい中毒症状を呈したことから断酒薬としての作用が発見されたという。
出典 株式会社平凡社世界大百科事典 第2版について 情報 |
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