Neurodermatitis - Neurodermatitis

Japanese: 神経皮膚炎 - しんけいひふえん

A type of skin disease. When allergic contact dermatitis occurs repeatedly in the same area, the epidermis thickens, edema and cellular infiltration occur in the dermis, and the skin appears thicker, forming an erythematous plaque with clearly accentuated skin grooves and ridges. This type of skin disease was once called neurodermatitis, perhaps because of the severe itching and the appearance of peripheral nerve involvement. Contact allergens that are likely to cause neurodermatitis include metals such as chromium, nickel, and cobalt, plant components that are exposed professionally (urushiol, alantolactone), and hair dyes and fragrances that are exposed by hairdressers and barbers. When a patch test is performed for the causative allergen, the primary skin rash that had improved temporarily may temporarily worsen.

Source: Heibonsha World Encyclopedia, 2nd Edition Information

Japanese:

皮膚病の一つ。アレルギー性接触皮膚炎が同一個所で反復して起こると，そこの表皮は肥厚し，真皮には浮腫や細胞浸潤が起こって，外見上皮膚は厚くなり，皮溝と皮丘がはっきりと強調されてみえる紅斑性局面をつくる。かゆみが強く，末梢神経が侵されているようにみえたためか，このような皮膚病をかつては神経皮膚炎といった。神経皮膚炎をつくりやすい接触アレルゲンは，クロム，ニッケル，コバルトなどの金属，職業的に触れる植物成分(ウルシオール，アラントラクトン)，美容師，理容師の触れるヘアダイ(毛染料)や香料などで，原因アレルゲンのパッチテストを行うと，いったんよくなっていた原皮疹が一時的に悪化をみることがある。

出典　株式会社平凡社世界大百科事典第２版について　情報

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