…Activated coagulation factors, especially complexes with phospholipids, are processed by reticuloendothelial cells and removed from the circulating blood. Antithrombin III, an anticoagulant, is present in plasma and neutralizes the activity of activated coagulation factors such as thrombin, activated factor IX, activated factor X, and activated factor XI. Heparin inhibits coagulation by significantly promoting the reaction of antithrombin III to neutralize these activated coagulation factors. … *Some of the terminology that mentions "Antithrombin III" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…活性化凝固因子とくにリン脂質との複合体は,網内系細胞によって処理され循環血中から除去される。血漿中には,アンチトロンビンIIIという凝固阻止因子が存在し,トロンビン,活性化IX因子,活性化X因子,活性化XI因子などの活性化凝固因子の活性を中和する。ヘパリンは,アンチトロンIIIのこれら活性化凝固因子を中和する反応を著しく促進することによって,凝固を阻止している。… ※「アンチトロンビン III」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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