ACTH preparations - ACTH preparations

Japanese: ACTH 製剤 - あくすせいざい
ACTH preparations - ACTH preparations

…Recently, research into the biosynthesis of ACTH has progressed, and it has become clear that ACTH, along with lipotropin, is produced from a common precursor with a larger molecular weight, and the entire amino acid sequence of that precursor has been determined.
[ACTH preparations]
The medicine ACTH is made from a peptide of 39 amino acids extracted from the anterior pituitary gland of herbivorous animals, or a synthetic peptide of 24 or 18 amino acids. The 24-amino acid peptide has the same amino acid sequence as the natural peptide from 1 to 24, while the 18-amino acid peptide has only the first amino acid different.

*Some of the terminology that refers to "ACTH preparations" is listed below.

Source | Heibonsha World Encyclopedia 2nd Edition | Information

Japanese:

…最近,ACTHの生合成に関する研究がすすみ,ACTHはリポトロピンなどとともに,さらに分子量の大きな共通の前駆体からつくられることが明らかとなり,その前駆体の全アミノ酸配列が決定されている。脳下垂体【石橋 みゆき】
[ACTH製剤]
 薬としてのACTHは,草食獣の脳下垂体前葉から抽出したアミノ酸数39のペプチド,あるいはアミノ酸数24または18の合成ペプチドが用いられている。24個のものは,そのアミノ酸配列は天然のものの1番から24番とまったく同じ,18個のものは1番だけが異なっている。…

※「ACTH 製剤」について言及している用語解説の一部を掲載しています。

出典|株式会社平凡社世界大百科事典 第2版について | 情報

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