…At the end of the 19th century, E. von Behring observed that when animals were repeatedly injected with bacterial toxins, sometimes even a small amount of the toxin, which was less than the lethal dose, caused severe shock symptoms. He thought that this was because the animals had become hypersensitive to the toxin, and named this state hypersensitivity (Überempfindlichkeit in German). It was later discovered that the phenomenon Behring observed was due to an allergic reaction to the toxin as an antigen. … *Some of the terminology explanations that mention "Überempfindlichkeit" are listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…19世紀末にE.vonベーリングが,動物に細菌の毒素をくりかえし注射していくと,ときに致死量以下のごく少量の毒素の注射で激しいショック症状をおこすことを観察し,それは動物がその毒素に対して過敏になっているためと考え,その状態をhypersensitivity(過敏状態。ドイツ語ではÜberempfindlichkeit)と名づけた。やがて,ベーリングが観察した現象は毒素を抗原としたアレルギー反応にもとづくものであることが判明した。… ※「Überempfindlichkeit」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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