…They act strongly on target lymphoid cells in very small amounts, inducing and regulating cellular immune responses. The main ones are macrophage (migration) inhibitory factor (MIF), leucocyte inhibitory factor (LIF), mitogenic factor (MF) that promotes lymphocyte division, lymphotoxin, etc., and sometimes also include interferon. In recent years, the term is often broadened to include monokines (also called interleukin-1) produced by macrophages and cytokines produced by non-lymphocytes. … *Some of the terminology that refers to "leucocyte inhibitory factor" is listed below. Source | Heibonsha World Encyclopedia 2nd Edition | Information |
…ごく微量で標的リンパ系細胞に強力に作用して,細胞性免疫応答を発現させたり調節したりする。おもなものにマクロファージ遊走阻止因子macrophage(migration)inhibitory factor(MIFと略記),白血球遊走阻止因子leucocyte inhibitory factor(LIFと略記),リンパ球の分裂を促進するマイトジェン因子mitogenic factor(MFと略記),リンホトキシンlymphotoxinなどがあり,インターフェロンをも含めることがある。なお,近年では広義にマクロファージが産生するモノカインmonokine(インターロイキンinterleukin‐1ともいう)や非リンパ球が産生するサイトカインcytokineなどをも含める場合が多い。… ※「leucocyte inhibitory factor」について言及している用語解説の一部を掲載しています。 出典|株式会社平凡社世界大百科事典 第2版について | 情報 |
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